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        您好,歡迎您來到中國醫學科學院輸血研究所!

        何苗—副研究員

        發布時間:2019-12-20 【字號: 瀏覽次數:
         \
        何苗,男,漢族。2009年畢業于四川大學生命科學學院,獲得理學博士學位?,F工作于中國醫學科學院輸血研究所,輸血傳染病中心,研究員,碩士生導師,協和青年教師聯盟理事。
        教育背景:
        2000.9~2004.7 就讀于四川大學生命科學學院,專業生物科學,獲得理學學士學位
        2004.9~2009.7 就讀于四川大學生命科學學院,專業動物學,獲得理學博士學位
        工作:
        2009.7至今,在中國醫學科學院輸血研究所工作,主要從事血液安全領域的研究。
        主要研究方向:
        1. 血液宏基因組學與病原微生物生物信息學研究
        2. 人類基因組與疾病相關性研究
        獲獎情況:
        1. 四川省科學技術進步獎,三等獎(2018-J-3-92-R02),我國血液安全關鍵技術及保障策略的研究與應用。
        承擔項目:
        1. 自然科學基金青年項目:獻血/漿人群中人細小病毒B19的親緣地理學與群體遺傳學研究,項目負責人,項目經費23萬元;
        2. 自然科學基金面上項目:HBV、HCV與HIV在重慶地區的遺傳多樣性、親緣地理學與群體遺傳學研究,項目主要研究者,合作方負責人,項目經費66萬元;
        3. 四川省科技廳應用基礎研究:基于深度測序方法檢測血液傳播新發病原體,項目負責人,項目經費10萬元;
        4. 四川省科技廳國際合作項目:中國多血液中心HIV感染獻血者研究,項目主要研究者,項目經費30萬元;
        5. 四川省科技廳重點研發項目:基于宏基因組和培養組深度測序方法建立的導致感染性不明原因發熱病原體的鑒定和用藥指導研究,項目經費20萬元;
        6. 國際合作項目:The Recipient Epidemiology and Donor Evaluation Study-III,項目中方協調員,項目經費約2000萬元。
         
        發表論文情況:
        1. Ling Pu, Zuoyi Jian, Fen Pan, Yang Geng, Miao He, Pu Liao. Comparative genomic analysis and multi-drug resistance differences of Acinetobacter baumannii in Chongqing, China. Infect Drug Resist. 2019 Sep 11; 12: 2827-2838. doi: 10.2147/IDR.S216745. eCollection 2019.
        2. Zhan Gao  Jing Liu  Ping Fu  Mei Huang  Ru'an Cao  Xiuqiong Wen  Chunhong Zhang  Tao He  Wei Mao  Dan Liao  Ling Ke  Yashan Yang  Miao He*  Yu Liu  Jingxing Wang  Roger Y. Dodd  Paul Ness  Hua Shan Estimation of hepatitis B–positive rates in Chinese blood donors by combining predonation and postdonation screening results. TRANSFUSION 2019;00;1–6. doi:10.1111/trf.15158 (Correspondence)
        3. P. Zeng, Q. Liao, Z. Gao, M. He* & X. Rong Sero-prevalence and viremia status of dengue virus among asymptomatic blood donors post epidemic outbreak in Chinese Guangzhou in 2015, Transfusion Medicine, 2018. (Correspondence)
        4. Ya-Ling Gao, Zhan Gao Miao He* and Pu Liao Infection status of human parvovirus B19, cytomegalovirus and herpes simplex Virus- 1/2 in women with first-trimester spontaneous abortions in Chongqing, China. Virology Journal (2018) 15:74
        5. Min Xu, Yashan Yang, Ya Zhou, Zhiyang Liu, Yu Liu, and Miao He* 2017 Metagenomics in pooled plasma, with identification of potential emerging infectious pathogens. TRANSFUSION, 2018 Mar; 58(3):633-637. (Correspondence)
        6. Guo Tao, Gao Yaling, Gao Zhan, Liao Pu, He Miao*. Human papillomavirus genotype distribution among HPV-positive women in Sichuan province, Southwest China. Arch Virol. 2018 Jan;163(1):65-72. (Correspondence)
        7. Z. Gao, Y. Zhang, Y. Yang, M. Xu,P. Liao, W. He, J. Xu, Y. Liu , M. He* 2017 Dengue virus infections among blood donors in Guangxi of China, 2013–2014. Transfusion Medicine, doi: 10.1111/tme.12448. (Correspondence)
        8. Zhan Gao, Yu Zhang, Hua Shan, Ling Shi, Jing Liu, Min Xu, Peibin Zeng, Yu Liu, and Miao He. A 30-year systematic review and meta-analysis of hepatitis B virus among blood donors in mainland China: revealing increase of new threats. TRANSFUSION 2017; 57; 1988–1997. (Correspondence)
        9. Zhang Y, Chen LM, He M*. Hepatitis C Virus in mainland China with an emphasis on genotype and subtype distribution. Virology Journal (2017) 14:41. (Correspondence)
        10. Zeng P, Liu Y, He M*, Wang J, Keating S, Mao W, et al. (2017) The infection staging and profile of genotypic distribution and drug resistance mutation among the human immunodeficiency virus-1 infected blood donors from five Chinese blood centers, 2012-2014. PLoS ONE 12(6): e0179328. (Correspondence)
        11. He M*, et al, The Impact of Emerging Infectious Diseases on Chinese Blood Safety, Transfus Med Rev, 31 (2017) 94–101.
        12. Wang M, Fu P, Yin Y, He M*, Liu Y. PLoS One. Acute, Recent and Past HEV Infection among Voluntary Blood Donors in China: A Systematic Review and Meta-Analysis. Plos One, 2016, 11 (9): e0161089. (Correspondence)
        13. Ya Zhou, Guohui Bian, Qiongxiu Zhou, Zhan Gao, Pu Liao, Yu Liu, and Miao He* 2015 Detection of Cytomegalovirus, Human Parvovirus B19, and Herpes Simplex Virus-1/2 in Women With First-Trimester Spontaneous Abortions. Journal of Medical Virology, 87:1749–1753 (Correspondence)
        14. Yu Liu, Peibin Zeng, Jingxing Wang, Gui Liu, Min Xu, Ling Ke, Miao He* and Zhong Liu, 2014 Hepatitis B virus infection in a cohort of HIV infected blood donors and AIDS patients in Sichuan, China. J Transl Med. 2014 Jun 12;12:164. (Correspondence)
        15. MY Ma, M He, LY Liao, YY Guo, DQ Yu, ZZ Xiong, Y Liu, PB Zeng, P Liao, Molecular epidemiology and population dynamics of Hepatitis B Virus in Dianjiang County, Chongqing, China. Arch. Virol. 2014 Jan; 159 (1): 117-24. (Equal contribution)
        16. Y Liu, HL Ma, SH Chen, JX Wang, G Liu, M Xu, L Ke, and M He*, 2013, Interleukin-28B genetic variations and spontaneous clearance of hepatitis C antibody–positive blood donors in China. Transfusion. 53: 2498-2504. (Correspondence)
        17. M He, J Zhu, L Ke, L Gao, ZH Pan, XH Yang, WP Li, HIV/Human parvovirus B19 co-infection in blood donors and clinical patients in Sichuan, China. Blood Transfusion, 2012; 10(4): 502-14.
        18. L Ke, M He, CQ Li, Y Liu, L Gao, F Yao, J Li, XH Bi, YL Lv, JX Wang, ML Hirsch, WP Li, 2011, The prevalence of human parvovirus B19 DNA and antibodies in blood donors from four Chinese blood centers. Transfusion, 51: 1909-1918. (Equal contribution)
        19. Fu P, Lv Y, Zhang H, Liu C, Wen X, Ma H, He T, Ke L, Wu B, Liu J, He M, Liao D, Wang J, Ness P, Liu Y, Shan H. Hepatitis C virus prevalence and incidence estimates among Chinese blood donors. Transfusion. 2019 Jul 4. doi: 10.1111/trf.15432.
        20. E. M. Bloch, Y. Yang, M. He, L. Tonnetti, Y. Liu, J. Wang, Y. Guo, H. Li, D. A. Leiby, H. Shan. A pilot serosurvey of Babesia microti in Chinese blood donors. Vox Sanguinis (2018)
        21. Wang M, He M, Wu B, Ke L, Han T, Wang J, Shan H, Ness P, Guo N, Liu Y, Nelson KE. The association of elevated alanine aminotransferase levels with hepatitis E virus infections among blood donors in China. Transfusion. 2017 Feb; 57(2): 273-279.
        22. Hongxue Li, Miao He, Peibin Zeng, Zhan Gao, Guohui Bian, Chunhui Yang, and Wuping Li, 2015, The genomic and seroprevalence of human bocavirus in healthy Chinese plasma donors and plasma derivatives. Transfusion, 55:154-163.
        23. Bian GuoHui, Yang Chunhui, He Miao, Wang Hong, Liu Jiaxin, Cao Ye, Yang Hong, Liu Zhong, Li Wuping, Three different bacterial detection systems for platelet concentrates under inter-laboratory conditions, Transfusion and Apheresis Science,2013, 49, 3, 600
        24. Zeng P, Liu Y, He M, Gao Z, Zhou Y, Bian G, et al. HIV-1 genotypic diversity and prevalence of drug resistance among treatment naive HIV-infected individuals in Chengdu of China. Virus Genes. 2013. DOI 10.1007/s11262-013-0958-3
        25. Li C, Xiao X, Yin H, He M, Li J, Dai Y, et al. Prevalence and prevalence trends of transfusion transmissible infections among blood donors at four Chinese regional blood centers between 2000 and 2010. J Transl Med. 2012; 10: 176.
        26. Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Julin Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J. Brooks Jackson, and Hua Shan. The human immunodeficiency virus-1 genotype diversity and drug resistance mutations profile of volunteer blood donors from Chinese blood centers. Transfusion. 2012; 52(5): 1041-9.
        27. Yu Liu, Jingxing Wang, Yi Huang, Tonghan Yang, Xiaoming Guo, Julin Li, Guoxin Wen, Zhongqiao Yun, Peibin Zeng, Miao He, Min Xu, Gui Liu, Ling Ke, David Wright, Jing Liu, Kenrad Nelson, Hua Shan. Molecular epidemiological study of hepatitis B virus in blood donors from five Chinese blood centers. Arch Virol. 2012; 157(9): 1699-707.
        28. M. He, J. C. Feng, S. Y. Liu, P. Guo, E. M. Zhao, 2009 The phylogenetic position of Thermophis (Serpentes: Colubridae), an endemic snake from the Qinghai-Xizang Plateau, China. Journal of Natural History, 43 (7&8): 479-488.
        29. M. He, J. C. Feng, E. M. Zhao, The complete mitochondrial genome of the Sichuan hot spring keel-back (Thermophis zhaoermii; Serpentes: Colubridae) and a mitogenomic phylogeny of the snakes. Mitochondrial DNA, 21(1): 8–18.
        30. 徐敏; 黃楊; 侯穎; 毛偉; 馬紅麗; 萬建華; 何偉蘭; 黃梅; 劉魚; 王憬惺; 何苗; 2018中國獻血人群感染巨細胞病毒CMV 的分子流行病學調查, 中國輸血雜志,31(5):42-65。
        31. 張玉; 高瞻; 楊亞閃; 何苗,2017,中國5個地區獻血人群HCV基因型分布及進化分析,中國輸血雜志,30(5):443-448。
        32. 胡珀璐;鮑晶晶;印澄;石潔;何苗; 2017,南京地區無償獻血人群HBV感染情況調查,中國輸血雜志,30(5):448-451。
        33. 黃梅;文秀瓊;曹汝安;高瞻;付萍;王憬惺;劉靜;山華;劉魚;何苗; 2017,綿陽地區無償獻血者中HBsAg真實流行情況調查:獻血前快檢以及獻血后篩查確證試驗結果聯合分析,中國輸血雜志,30(5):451-453。
        34. 許紀玲;蔡杰;何苗;楊永林;2017,HEV保護性抗體的制備與功能研究,中國輸血雜志,30(5): 459-462。
        35. 蔡杰;許紀玲;何苗;楊永林;2017,獻血者HEV感染后VP13抗體的免疫應答研究,中國輸血雜志,30(5):466-469。
        36. 高瞻;張玉;楊亞閃;徐敏;何苗; 2017,熒光定量檢測梅毒篩查陽性獻血者中生殖器潰瘍病原體的研究,中國輸血雜志,30(5):470-472。
        37. 徐敏;毛偉;何濤;張春紅;衛昱燕;高瞻;張玉;何苗; 2017,重慶地區健康獻血人群弓形蟲抗體檢測結果分析,中國輸血雜志,30(1):58-60。
        38. 徐敏,毛偉,何濤,衛昱燕,高瞻,張玉,張春紅,廖紅梅,劉魚,曾沛斌,王憬惺,何苗,2016,重慶地區健康獻血人群血液宏基因組分析與新發病原體鑒定,中國輸血雜志,29(9):895-898。
        39. 侯穎,高瞻,徐敏,張玉,何苗,2016,我國部分地區獻血人群中單純皰疹病毒感染流行情況,中國輸血雜志,2016,29(4):397-399。
        40. 邊國慧,楊春暉,高瞻,徐敏,何苗,2015,梅毒螺旋體-15 脂蛋白的原核表達及其純化,中國生物制品學雜志,28(8):800-803。
        41. 邊國慧,楊春暉,高瞻,徐敏,何苗,2015,一種新的實時熒光定量PCR 方法對血小板制品細菌污染檢測效果的評價,中國輸血雜志,28(4):387-390。
        42. 李佳凌, 巫岳龍, 鄒禮樂, 蔡延森, 何苗, 2015, 血液中檢測人巨細胞病毒的熒光定量PCR 方法建立及評估, 中國輸血雜志,28(6):637-641。
        43. 何偉蘭,李聚林,許建榮,周仲民,龐志向,鄧瓊,謝文英,劉振北,王憬惺,何苗,2013,柳州地區無償獻血者HBV 遺傳分化情況調查,中國輸血雜志,26(11):1067-1070。
        44. 何偉蘭,高瞻,許建榮,李聚林,周仲民,龐志向,鄧瓊,謝文英,劉振北,王憬惺,何苗,2013,柳州地區無償獻血者獻血前淘汰原因分析,中國輸血雜志,26(11):1071-1072。
        45. 何苗,高蕾,柯玲,劉魚,曾沛斌,李武平,2011,中國人細小病毒B19系統發育關系研究,中國輸血雜志,24(5):399-402。
        46. 何苗,柯玲,李武平,2010,中國獻血人群中人細小病毒B19的分子流行病學調查,中國輸血雜志,23(10):890-891。
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